Japanese Center for the Validation of Alternative Methods
Office : New Testing Method Assessment, Division of Pharmacology,
National Biological Safety Research Center (NBSRC),
National Institute of Health Sciences (NIHS)

JaCVAM Activities

2009 Academic activities

-- 2012 　-- 2011 　-- 2010 　→ 2009 　<Articles> <Presentations, Speeches> 　-- 2008 　-- 2007 　-- 2006

Articles

Presentations, Speeches

-- 2009

• Kojima, H., Current aspects of LLNA-DA and LLNA-BrdU as alternatives for skin sensitizer classification in Japan, 2009 Winter Conference of　Korean Society of Alternatives to Animal Experiments, Seoul (February, 2009)
• R Tice, F Deal, P Ceger, D Allen, J Gordon, J DeLange, S Bremer, M Nakamura, H Kojima, A Ono and W Stokes: Establishing a Historical Database for a Multi-phased International Validation Study of a Stably-Transfected Estrogen Receptor (ER) Transcriptional Activation (TA) Test Method, 48th Annual SOT meeting, Baltimore (2009)
• J Strickland, M Paris, D Allen, R Tice, H Kojima, P Prieto, M Wind and W Stokes: ICCVAM/NICEATM/ECVAM/JaCVAM Scientific Workshop on Acute Chemical Safety Testing: Advancing In Vitro Approaches and Humane Endpoints for Acute Systemic Toxicity Evaluations, 48th Annual SOT meeting, Baltimore (2009)
• Kojima, H.：3D comet assay, JaCVAM experience, 5th International Workshop on Genotoxicity Testing, Basel (2009)
• Kojima, H., Yamakage, K., Burlinson, B., Escober, P., Pant, K., Kraynak, A., Hayashi, M., Corvi, R., Uno, Y., Schechtman, L., Tice, R. and Honma, M.: International validation study of the in vitro alkaline comet assay, 8th International Comet Assay Workshop, Perugia (2009)
• Nakajima, M., Masumori, S., Tanaka, J., Hayashi, M., Uno, Y., Kojima, H. and Tice, R.: An atlas of comet images: JaCVAM initiative International Validation trial for the in vivo comet assay, 8th International Comet Assay Workshop, Perugia (2009)
• Kojima, H.：Validation of innovative methods for safety testing: drawbacks and advantages of Japanese validation studies, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Kojima, H., Matsui, T., Kohara, A., Yoshida, A. and Nakamura, Y.: GCCP initiatives in Japan, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Ono, A., Takeyoshi, M., Bremer, S., Jacob, M., Laws, S., Sozu, T. and Kojima, H.: The International validation study for the ER alpha STTA antagonist assay using HeLa9903, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Allen, D., Deal, F., Ceger, P., Gordon, J., Pazos, P., deLange, L., Bremer, S., Nakamura, M., Kojima, H., Ono, A., Tice, R. and Stokes W.: Testing of coded substances for a multi-phases international validation study of an estorogen receptor (ER) transcriptional activation (TA) assay, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Kojima, H., IIjima, M., Matsunaga, K., Sasa, H., Itagaki, H., Okamoto, Y., Nishiyama, N., Mita I., Washida, J., Masuyama, K., Onodera, H., Masuda, M. and Ohno, Y.: Review of an alternative to animal testing for safety evaluation of cosmetic ingredients using Quasi-drug, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Wind, M., Blakey, D., Kojima, H., Kreysa, J. and Stokes, W.: What is the international cooperation on alternative test methods (ICATM) and what is its role?, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Kojima, H.：JaCVAM’s role in the 3Rs and ICATM, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Kojima, H.：Recent progress and future directions at JaCVAM, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Inoue, T., Masuda, M., Akita. M., Kojima, H. and Ohno, Y.: JaCVAM statement on new alternative to animal testing, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Takeyoshi, M., Kojima, H., Omori, T., Sozu, T. and Yoshimura, I.: Validation study for non-radioisotopic local lymph node assay based on BrdU incorporation (LLNA-BrdU), 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Kojima, H., Ando, Y., Yamaguchi, Y., Kosaka, T., Suzuki, T., Yuasa, A., Watanabe, Y., Shinoda, S., Idehara, K., Yoshimura, I., Miyaoka, E., Ishiyama, K., Kato, M. and Omori, T. : Validation of LabCyte EPI-MODEL24, an In Vitro Assay for Detecting Skin Irritants, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Yamamoto, N., Hirano, K., Kato, M., Hata, K., Horiguchi, M., Taniguchi, K. and Kojima, H.: Cell surface maker of corneal epithelium stem cells and culture, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Lowther, D., Wind, M., Stokes, W., Barroso, J., Zuang, V., Amcoff, P., Kojima, H., Prinsen, M., Tice, R., Allen, D. and McCall, D.: International acceptance of in vitro alternative ocular safety testing methods: the isolated chicken eye (ICE) test method (Draft OECD TG 438), 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Merrill, J., Wind, M., Stokes, W., Barroso, J., Zuang, V., Amcoff, P., Kojima, H., Jacobs, A., McCall, D. Allen D. and Tice, R.,: International acceptance of in vitro alternative ocular safety testing methods: bovine corneal opacity and permeability (BCOP) test method (Draft OECD TG 437), 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Hayashi, M., Uno, Y., Honma, M., Schectmann, L., Tice, R., Corvi, R., Morita, T., Asano, N. and Kojima, H.: In vivo Comet Assay: Update on the on-Going international validation study, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Honma, M., Kojima, H., Morita, T., Uno, Y., Asano, N., Nakajima, M., Corvi, R., Tice, R., Schectman, L. and Hayashi, M.: Intenational validation study of the in vitro alkaline comet assay, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Kojima, H., Arai S. and Hojyo M.: Adequate conditions for performance of comet assay using 3-dimensional human epidermal model, 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Stokes, W., Wind, M., Matheson, J., Jacob., A., Casati, S., Kojima, H., Allen, D., Burns, T., Salicru, E., Strickland, J. and Tice, R., Internationally harmonized performance standards (PS) for the murine local lymph node assay (LLNA), 7th World Congress on Alternatives & Animal Use in the Life Sciences, Rome（2009）
• Honma, M., Kojima, H., Morita, T., Uno, Y., Asano, N., Nakajima, M., Corvi, R., Tice, R., Schectman, L. and Hayashi, M.: Intenational validation study of the in vitro alkaline comet assay, 25th ICEM , Florence（2009）
• Uno, Y., Kojima, H., Honma, M., Schectmann, L., Tice, R., Corvi, R., Morita, T., Asano, N. and Hayashi, M.: In vivo Comet Assay: Update on the on-Going international validation study, 25th ICEM , Florence（2009）
• Hajime Kojima: Japanese views in the 3Rs in the 21st century, ZEBET's 20th Anniversary Symposium, Berlin, Germany (2009)
• Hajime Kojima: Organization of JaCVAM and its activity, KoCVAM International Symposium and 6th Congress of KSAAE, Seoul (2009)
• Hajime Kojima: Utilization of an alternative to animal testing for safety evaluation of cosmetic ingredients using Quasi-drug, The 17th ICDS (International Contact Dermatitis Symposium) and the 10th APEODS (Asia-Pacific Environmental and Occupational Dermatology Symposium), Kyoto (2009)
• Hajime Kojima:Japanese approach to regulatory acceptance of new skin sensitization testings with due considerations to animal welfare and 3Rs, The 17th ICDS (International Contact Dermatitis Symposium) and the 10th APEODS (Asia-Pacific Environmental and Occupational Dermatology Symposium), Kyoto (2009)