Japanese Center for the Validation of Alternative Methods
Office : New Testing Method Assessment, Division of Pharmacology,
National Biological Safety Research Center (NBSRC),
National Institute of Health Sciences (NIHS)

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Information on OECD Guidelines

Information on OECD Guidelines

OECD Guidelines for the Testing of Chemicals

http://masetto.sourceoecd.org/vl=5699750/cl=17/nw=1/rpsv/cw/vhosts/oecdjournals/
1607310x/v1n4/contp1-1.htm

List of the Alternative methods on OECD guideline (except the Genotoxicity test)

No.	Test name	Adapted date
428	In Vitro Skin absorption	Updated Guideline, adopted 24th April 2002
429	Skin Sensitisation: Local Lymph Node Assay	Updated Guideline, adopted 24th April 2002
430	In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER)	Original Guideline, adopted 13th April 2004
431	In Vitro Skin Corrosion: Human Skin Model Test	Original Guideline, adopted 13th April 2004
432	In Vitro 3T3 NRU Phototoxicity Test	Original Guideline, adopted 13th April 2004
437	Bovine Corneal Opacity and Permeability (BCOP) Test Method for Identifying Ocular Corrosives and Severe Irritants	Original Guideline, adopted 7th September 2009
438	Isolated Chicken Eye (ICE) Test Method for Identifying Ocular Corrosives and Severe Irritants	Original Guideline, adopted 7th September 2009
439	In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method	Original Guideline, adopted 22nd July 2010
442a	Skin Sensitization: Local Lymph Node Assay: DA	Original Guideline, adopted 22nd July 2010
442b	Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA	Original Guideline, adopted 22nd July 2010
455	Stably Transfected Human Estrogen Receptor-α Transcriptional Activation Assay for Detection of Estrogenic Agonist-Activity of Chemicals	Original Guideline, adopted 1st April 2009
487	In Vitro Mammalian Cell Micronucleus Test	Original Guideline, adopted 22nd July 2010

Correlation with OECD test guideline

Project 4.34	EDTA Activity - New TG for a stably Transfected Transcriptional Activation (STTA) Assay for the detection of anti-estrogenic activity of chemicals
Project 4.36	New TG: Comet Assay in Genotoxicity Testing
Project 4.26	Cell Transformation Assay using Balb/c 3T3 cell line
Project 4.35	New TG for an In Vitro Skin Irritation Assay (LabCyte model)
TG429	Skin Sensitisation for a Non-Radioisotope version of the Local Lymph Node Assay