Japanese Center for the Validation of Alternative Methods
Office : New Testing Method Assessment, Division of Pharmacology,
National Biological Safety Research Center (NBSRC),
National Institute of Health Sciences (NIHS)

JaCVAM Activities

2007 Academic activities

-- 2012 　-- 2011 　-- 2010 　-- 2009 　-- 2008 　→ 2007 　<Articles> <Presentations, Speeches> 　-- 2006

Articles

-- 2007

• Hirabayashi Y, Inoue T. Implications of hemopoietic progenitor cell kinetics and experimental leukemogenesis: Relevance to Gompertzean mortality as possible hematotoxicological endpoint. Exp Hematol 35:125-133, 2007

Presentations, Speeches

-- 2007

• Kenji Idehara, Takashi Omori, Hajime Kojima, Takashi Sozu, Kazunori Arima, Hirohiko Goto, Tomohiko Hanada, Yoshiaki Ikarashi, Taketo Inoda, Yukiko Kanazawa, Tadashi Kosaka, Eiji Maki, Takashi Morimoto, Shinsuke Shinoda, Naoki Shinoda, Masahiro Takeyoshi, Masashi Tanaka, Mamoru Uratani, Masahito Usami, Atsushi Yamanaka, Tomofumi Yoneda, Isao Yoshimura, Atsuko Yuasa, Validation of LLNA-DA assay for assessing skin sensitization potential, 46th SOT, North Carolina (2007)
• WS Stokes, S Bremer, M Jacobs, H Kojima, J Kanno, P Ceger, FH Deal, RR Tice, NICEATM/ECVAM/JaCVAM Multi-phased International Validation Study of a Stably-Transfected Estrogen Receptor (ER) Transcriptional Activation (TA) Test Method. 46th SOT, North Carolina (2007)
• Kojima, H., JaCVAM Update, Scientific Advisory Committee on Alternative Toxicological Methods, Bethesda, (June, 2007)
• Kojima, H. JaCVAM Update, 6th　World Congress on Alternatives 6 Animal Use in the Life Sciences, p.119,Tokyo (2007)
• Kojima, H. JaCVAM Process to Validate and Peer Review of New Alternative Methods, 6th　World Congress on Alternatives 6 Animal Use in the Life Sciences, p.82, Tokyo (2007)
• Kojima, H. Validation study using Japanese models, 6th　World Congress on Alternatives 6 Animal Use in the Life Sciences, p.64, Tokyo (2007)
• Arai, S., Yamamoto, N. and Kojima, H., Safety evaluation test using a human cultured epidermal model- with the ECVAM validation proposal and chemicals-, 6th　World Congress on Alternatives 6 Animal Use in the Life Sciences, p.224. Tokyo (2007)
• Kojima, H., Arai, S., Kubo, K. and Kato M., Dose-response evaluation using a coreal model, an alternative to Draize eye irritation testing, 6th　World Congress on Alternatives & Animal Use in the Life Sciences, p.223,Tokyo (2007)
• Yamamoto, N, Kojima, H., Tanikawa, A. and Horiguchi, M., A study of retinal regulative medicine by human iris tissue cells, 6th　World Congress on Alternatives & Animal Use in the Life Sciences, p.103, Tokyo (2007)
• Yoshiaki Ikarashi, Takashi Omori, Yukiko Kanazawa, Kenji Idehara, Hajime Kojima, Takashi Sozu, Kazunori Arima, Hirohiko Goto, Tomohiko Hanada, Taketo Inoda, Tadashi Kosaka, Eiji Maki, Takashi Morimoto, Shinsuke Shinoda, Naoki Shinoda, Masahiro Takeyoshi, Masashi Tanaka, Mamoru Uratani, Masahito Usami, Atsushi Yamanaka, Tomofumi Yoneda, Isao Yoshimura and Atsuko Yuasa, First Inter-laboratory validation study on LLNA-DA, 6th　World Congress on Alternatives 6 Animal Use in the Life Sciences, p.254, Tokyo (2007)
• Yukiko Kanazawa, Takashi Omori, Yoshiaki Ikarashi, Kenji Idehara, Hajime Kojima, Takashi Sozu, Kazunori Arima, Hirohiko Goto, Tomohiko Hanada, Taketo Inoda, Tadashi Kosaka, Eiji Maki, Takashi Morimoto, Shinsuke Shinoda, Naoki Shinoda, Masahiro Takeyoshi, Masashi Tanaka, Mamoru Uratani, Masahito Usami, Atsushi Yamanaka, Tomofumi Yoneda, Isao Yoshimura and Atsuko Yuasa, Second Inter-laboratory validation study on LLNA-DA, 6th　World Congress on Alternatives 6 Animal Use in the Life Sciences, p.255, 6th　World Congress on Alternatives 6 Animal Use in the Life Sciences, Tokyo (2007)
• Takashi Omori, Yoshiaki Ikarashi, Yukiko Kanazawa, Kenji Idehara, Hajime Kojima, Takashi Sozu, Kazunori Arima, Hirohiko Goto, Tomohiko Hanada, Taketo Inoda, Tadashi Kosaka, Eiji Maki, Takashi Morimoto, Shinsuke Shinoda, Naoki Shinoda, Masahiro Takeyoshi, Masashi Tanaka, Mamoru Uratani, Masahito Usami, Atsushi Yamanaka, Tomofumi Yoneda, Isao Yoshimura and Atsuko Yuasa, Validation studies on LLNA: Importance of study management,　 6th　World Congress on Alternatives & Animal Use in the Life Sciences, p.264, Tokyo (2007)
• Stokes, W. S., Bremer, S., Jacobs, M., Ono A., Kojima, H., Ceger, P., Deal F. and Tice, R., NICVEATM/ECVAM/JaCVAM Multi-phase International validation study of an in vitro estrogen receptor transcriptional activation assay to detect agonist and antagonist activity, 6th　World Congress on Alternatives & Animal Use in the Life Sciences, p.265, Tokyo (2007)
• Kojima, H., JaCVAM Update, ECVAM Scientific Advisory Committee, Ispra (November ,2007)
• Kojima, H., International Validation Study of Non Animal Screening Assay for Endocrine Disrupter、2007　National Institute of Toxicological　Research　International　Symposium, Korea（2007）
• Arai, S., Saitou, M., Takashima, Y. Honma, M. and Kojima, H., Anew trial for in vitro Comet assay using a 3-dimensional human epidermal model, 36th Annual Meetings of the Japanese Environmental Mutagen Society, Kitakyusu (2007)
• Kojima, H., et al, Validation and implementation, Round table on International aspects of validation & accept, Regulatory Acceptance and Implementation of 3R approach, Annual Conference 2007 EPAA, Brussels (2007)