Japanese Center for the Validation of Alternative Methods
Office : New Testing Method Assessment, Division of Pharmacology,
National Biological Safety Research Center (NBSRC),
National Institute of Health Sciences (NIHS)

About JaCVAM

Glossary

3Rs:

Reduction of animal use.
Refinement to lessen pain or distress and to enhance animal well-being.
Replacement of an animal test with one that uses non-animal systems or phylo-genetically lower species.

For more detail on 3Rs, please refer to OECD Guidance document 34.

Link

• http://www.oecd.org/LongAbstract/0,3425,en_2649_34377_35250955_1_1_1_37407,00.html